Overview of Bio-Atlas efforts
The atlas project was originally focused on the microanatomy of zebrafish and humans, viewable as virtual slides. The content is being re-organized to have subsections devoted to zebrafish, humans, mice, and other model systems. We are working on ways to present microCT-based 3D histology. We welcome ideas and high-resolution slides and images from the community and are seeking collaborations that would make the resource more valuable.
The Bio-Atlas is organized with subsections devoted to humans, zebrafish, mice, and other model systems. The project was originally focused on the microanatomy of zebrafish. To address the need for a more human orientation, we introduce the Bio-Atlas as a platform for coordination of data between human and other model systems.
Since pathophysiological mechanisms in humans are reflected in tissue architecture, morphological changes in the best models of human disease will involve similar phenotypes as in humans. We welcome ideas and high-resolution 2D and 3D images from the community and are seeking collaborations to expand this resource.
'Comparative analysis of fixation and embedding techniques for optimized histological preparation of zebrafish. Copper JE, Budgeon LR, Foutz CA, van Rossum DB, Vanselow DJ, Hubley MJ, Clark P, Mandrell DT, Cheng KC. Comp Biochem Physiol C Toxicol Pharmacol. 2018 Jun;208:38-46. doi: 10.1016/j.cbpc.2017.11.003. Epub 2017 Nov 20. PMID: 29157956